The contractile ring

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The contractile ring

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The contractile ring

What is the contractile ring? During cell division, the contractile ring generates the constricting force to separate one cell into two cells. Formed during cytokinesis, the last step of cell division, the contractile ring is composed of filamentous actin (F-actin) and the motor protein myosin-2, along with additional structural and regulatory proteins. The contractile ring forms under the surf...

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Molecular model of the contractile ring.

We present a model for the actin contractile ring of adherent animal cells. The model suggests that the actin concentration within the ring and consequently the power that the ring exerts both increase during contraction. We demonstrate the crucial role of actin polymerization and depolymerization throughout cytokinesis, and the dominance of viscous dissipation in the dynamics. The physical ori...

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A Molecular Model of the Contractile Ring

We present a model for the actin contractile ring of adherent animal cells. The model suggests that the actin concentration within the ring, and consequently the power that the ring exerts both increase during contraction. We demonstrate the crucial role of actin polymerization and depolymerization throughout cytokinesis, and the dominance of viscous dissipation in the dynamics. The physical or...

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Assembly of ring canals in the male germ line from structural components of the contractile ring.

Stable intercellular bridges called ring canals form following incomplete cytokinesis, and interconnect mitotically or meiotically related germ cells. We show that ring canals in Drosophila melanogaster males are surprisingly different from those previously described in females. Mature ring canal walls in males lack actin and appear to derive directly from structural proteins associated with th...

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ژورنال

عنوان ژورنال: Current Biology

سال: 2003

ISSN: 0960-9822

DOI: 10.1016/j.cub.2003.08.038